Radiolab

Monthly Archives: April 2008

What is fMRI and what is it measuring?

April 30, 2008 – 6:00 am

Hemoglobin

BerserkerBen/wikimedia (Click to view animation)

As Radio Lab explores some of the tangents from our show on Deception, we’ve interviewed neuroscientists attempting to detect lies using changes in brain activity. But how do we see brain activity and get such colorful pictures of it? You might think it’s based on neural electric activity. This is true for EEG but not for fMRI, which is used in the majority of these brain function studies. As Wired.com’s Steve Silberman explains, it all starts with hemoglobin. Yes, the tiny protein responsible for carrying oxygen to the brain or any other organ for that matter, is the basis for studying brain activity.

To get a better sense of how hemoglobin tells us what we’re thinking about, Silberman goes to Professor Joy Hirsch’s lab at Columbia to see exactly what goes into these studies of lie detection.

Listen to this clip of Robert’s interview with Steve Silberman:

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Where do lies come from?

April 28, 2008 – 6:00 am

We interviewed Dan Langleben while researching for our show on Deception. He says he can see differences in brain activity when a lie is told about a playing card in your pocket. He identified a few regions in the brain that changed in metabolism during a lie. That is, it seemed as though it took more energy for the brain to lie.

The exact functions of these brain regions can be controversial but they may be involved in deception:
Langleben3

IFC, Inferior frontal gyri or Inferior frontal Cortex (semantics and control over behavior)
Premotor Cortex (activate motor activity through the primary motor cortex)
ACC, Anterior Cingulate Cortex (reward, decisions, empathy)
Fusiform gyrus or body (face recognition)

Listen to Dan Langleben talking to Jad about these brain regions:

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Pre-911, before Dr. Langleben received heaps of money to study deception, he studied children with ADD. Here he discusses the connection between two seemingly disconnected areas of research and the improvements in the technology that made his transition possible:

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In his study, Langleben was careful to control for “salience”. This means he wanted to make sure the brain activity he saw wasn’t just due to excitement in seeing the card in their pocket. But there may also be some usefulness for this control:

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The Fifth Annual Bent Festival hath begun!

April 25, 2008 – 2:27 pm

bentfestival.jpg


Gearheads, take note! The Bent Festival is in NYC all weekend long!

It’s a three day-long exploration of hardware hacking, DIY electronics, and circuit bending. Artists from around the globe perform music with their homemade or circuit bent instruments each night of the festival, teach workshops to adults and children alike, and create amazing, interactive art installations. The festival brings together artists of all ages and showcases the state of the art of DIY electronics and circuit bending culture.

Dates:
April 24-26

Location:
DCTV
87 Lafayette St
New York, NY, 10013

Tickets:
Each concert is $10.
A Festival Pass to all events is available for $25.

If you can’t make it to New York, the Bent Festival is also coming to Minneapolis May 1st-3rd.

For more information go here.

Free Joy!

April 25, 2008 – 11:30 am

happy-pills.jpg

Last month, a report came out detailing some of the ways in which expectations affect our responses to pain medications. And according to an article about this report in The Baltimore Sun, one factor that influences our expectations is price. The article goes on to explain that two groups of test volunteers were given placebos after receiving an electric shock. One group was told the placebo pills they were given cost 10 cents each. The other group was told each pill cost $2.50. 85% of the volunteers in the $2.50 group reported pain reduction with the placebo, while only 60% of the volunteers in the 10-cent group did.

We hope the fact that this joyful ringtone (from Placebo) is free won’t make you less likely to get a kick out of it.

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My kid the bioengineer

April 23, 2008 – 6:00 am

marj_k Aequorea

marj k/flickr

In our show (So Called) Life, we interviewed undergrads at MIT giving bacteria genes to make them smell minty fresh. If you are at all disquieted that such young minds are given such profound tools, sorry, bioengineers are getting ever younger..

As part of a program designed to help teachers in NYC schools run a DNA transformation lab, I’ve seen 5th graders engineer bacteria to glow like a certain species of jellyfish found off the coast of Washington State.

These 10-year-olds readily absorb the concept that the DNA code is universal and that bacteria swap and take up bits of DNA in the form of plasmids. Using this information, they predicted the expected results before the experiment. “Why shouldn’t bacteria glow in the dark?” they said. “As long as they have the instructions, it’s easy!”

Tell us what your little scientists are doing these days!

Pop Music

April 22, 2008 – 1:46 am

poprecord.jpg

Why do some songs mercilessly stick in our heads and repeat themselves over and over? What makes these hooks so hooky? And how does a songwriter will a song forth from the ether? In this episode, nightmarish stories of musical hallucinations, songs that transcend language, and the triumphant return of the Elvis of Afghanistan.

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Getting Older Every Year

April 21, 2008 – 3:29 pm

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In light of Jad’s recent birthday, we thought we’d share this video. It’s sort of like a video version of “Nancy Grows Up” from our Time episode.

HAPPY BIRTHDAY, JAD!!!

April 18, 2008 – 9:54 am

Jad at Blue Spoon

It’s Jad’s birthday today.

If you want to make him happy, here’s what you can do. He’s got a mocha addiction that you can help support. Send a Starbuck’s gift card to:
Jad Abumrad
Host/Creator/Producer, Radiolab
WNYC
1 Centre Street
New York, NY 10007

If everyone pitches in, I’m sure we can make season 5 in full alertness!

Send your birthday wishes to: radiolab@wnyc.org.

Panta Rei

April 18, 2008 – 6:00 am

stained2.jpg
Atelier Teee/flickr

Greek philosopher Heraclitus said “Panta Rei”, which means “all things flow”.

Rheology (”flow”-ology) is the study of viscoelastic materials like Jello that are a little bit liquid and a little bit solid. But even the most liquid of liquids have some solid character. And even the most solid of solids have some liquid character. Take those beautiful stained glass windows in gothic cathedrals. For a long time it was thought that these windows are thin at the top and thick at the bottom as a result of centuries of slow viscous flow. As it turns out, it would take much more than centuries for glass to flow (see comments below).

But as we saw in our show (So-Called) Life, scientific observation soon turns to manipulation. In the world of biomechatronics, scientists are using “magnetorheologic” fluids to emulate the complex motions of human limbs to help victims of trauma, disease or birth defects.

Watch the closely related “ferrofluid” in action.

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Luke28OR/Youtube

Reflecting on Heraclitus’ statement, Marcus Reiner, one of the fathers of modern rheology said “Everything will flow. You just have to wait long enough.”

Tell us what’s begun to flow in your life..

Climate change and critical thinking

April 16, 2008 – 1:24 pm

globaltempmap.jpg
yeimaya/flickr

NPR’s David Kestenbaum ran a piece yesterday on Morning Edition about a 16-year-old climate skeptic named Kristen Byrnes. This ambitious teenager has set up a website and dedicated huge chunks of her time to arguing that the rise of global temperature is part of a natural cycle and not, as most climate scientists agree, caused by human action.

The debate about the piece swirling around the science blog world provides a fascinating view into questions of expertise, critical thinking, and role of the media in covering the issue of climate change.

Kestenbaum draws us into what seems like a feel-good story about a young girl who has done something rather unusual. But his piece is really about much larger, and much more complicated issues: We’re not all scientists, so we have to look to others for expertise. At the same time, we should be critical in the face of that expertise.

Perhaps Kristen is a good example of critical thinking; as Kestenbaum says, “Kristen has a quality you want in a scientist, she is skeptical.” And she definitely tackled a pile of data and technical information that most teenagers would balk at. But Kristen may also have some qualities you don’t want in a scientist, particularly if she’s just seeking out evidence that supports her prior beliefs. She herself says “I never really believed in it.” And some of her science is questionable.

Toward the end of the piece, Kestenbaum does point out that “the overwhelming consensus is that humans are causing global warming, and the consequences could be serious.” Many of the science bloggers argue that Kestenbaum was wearing kid gloves during this interview. But then again, Kristen is a kid. And, in the end, maybe Kestenbaum is making a more subtle point. While the discussion of hard science is somewhat absent, the story takes us to the true front lines of the climate debate: the hearts and minds of Americans who have a lay person’s understanding of climate science and how to evaluate complicated scientific evidence.

Check out the story and the bloggers’ response, then come back to us and let us know what you think.


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